Erscheinungsdatum: 28.09.2015, Medium: Taschenbuch, Einband: Kartoniert / Broschiert, Titel: Regio- and Stereoselective Catalytic Addition of Amides to Alkynes, Titelzusatz: Synthesis of the enamide substructure in the most atom-economic and environmentally friendly way, Autor: Blanchot, Mathieu, Verlag: Südwestdeutscher Verlag für Hochschulschriften AG Co. KG, Sprache: Deutsch, Rubrik: Organische Chemie, Seiten: 228, Informationen: Paperback, Gewicht: 356 gr, Verkäufer: averdo
Metallocenes in Regio- and Stereoselective Synthesis ab 352.99 € als Taschenbuch: Softcover reprint of hardcover 1st ed. 2005. Aus dem Bereich: Bücher, Wissenschaft, Technik,
Regio- and Stereoselective Catalytic Addition of Amides to Alkynes ab 89.9 € als Taschenbuch: Synthesis of the enamide substructure in the most atom-economic and environmentally friendly way. Aus dem Bereich: Bücher, Wissenschaft, Chemie,
Metallocenes in Regio- and Stereoselective Synthesis ab 352.99 EURO Softcover reprint of hardcover 1st ed. 2005
Regio- and Stereoselective Catalytic Addition of Amides to Alkynes ab 89.9 EURO Synthesis of the enamide substructure in the most atom-economic and environmentally friendly way
The primary objective of this project was the exploration of the rhodium(II) (N- dodecylbenzenesulfonyl)-prolinate (Rh2(DOSP)4) catalyzed decomposition of donor/acceptor substituted diazo compounds in the presence of a mixture of E/Z dienes. The dienes in the project are provided by the enyne metathesis between various alkynes and vinyl ethers. The reaction generally displays a slight preference for the formation of E-dienes. In this project, the intermolecular tandem cyclopropanation/Cope rearrangement reaction between vinylcarbenoids and dienes was used to synthesize cycloheptadienes asymmetrically. High levels of asymmetric induction were observed with aryl substituted vinylcarbenoids. The reaction achieves high diasteroselectivity at room temperature. With the increase of the size of the 3-substituent, a highly regio- and enantioselectivity reaction was achieved. The reaction not only discriminates the diene topology, but also differentiates the propargylic stereochemistry in an effective kinetic resolution. By combining the reaction with the intermolecular enyne metathesis, a highly stereoselective synthesis of complex cycloheptadienes can be achieved.
An essential reference book for all synthetic organic chemists The exceptionally useful chemical-reducing properties of organosilicon hydrides have been known for more than half a century. Since the early discovery of these properties, interest in the use of organosilicon hydrides for the reduction of organic functional groups has increased steadily and has led to the development of many techniques for their deployment in chemo-, regio-, and stereoselective transformations in organic synthesis. Ionic and Organometallic-Catalyzed Organosilane Reductions provides an up-to-date, comprehensive survey of the literature of this rich chemistry as it pertains to organic synthesis. Both ionic and catalyst-mediated reaction types are included, with appropriate reference to reaction mechanisms where they have been elucidated. A wide variety of organic functional group reductions by organosilicon hydrides receive critical comments and evaluation, especially with respect to scope and limitations. A substantial discussion of asymmetric reductions is also included in this book. The contents of the book are taken from the comprehensive review of the topic contained in the Organic Reactions series and cover the reduction of all organic groups. All known examples are compiled in thirty-four easily scanned, comprehensive tables compiled from 809 original articles. Updated lists comprising 256 additional references for the tables are provided that bring the coverage up to March 2009. The authors have been, and continue to be, involved in the applications of organosilanes to organic synthesis. Consistent with the goal of Organic Reactions, the content and presentation of this text emphasize the preparative aspects of the reductions focusing on the scope and limitations of the individual transformations along with detailed experimental procedures. Ionic and Organometallic-Catalyzed Organosilane Reductions is an essential reference book for all synthetic organic chemists working in academic and industrial laboratories.